FUNCTIONAL GLYCOGEN-BASED POLYMERS FOR ANTIBACTERIAL ACTIVITY
Glycogen, maleic anhydride, thionyl chloride, triethylamine and (amino pharmaceuticals such benzocaine, trimethoprim, sulfadiazine, mefenamic acid, and ciprofloxacin) were reacted under certain circumstances to create new medicinal polymers [FA1-FA5]. The prepared pharmaceutical polymers were characterized using FTIR and 1H NMR techniques. Additionally, the physical properties of the polymers were evaluated, including swelling, solubility, viscosity, and controlled drug release at pH values of 2, 7, and 8. The antibacterial properties of the synthesized polymers were studied, the disk-diffusion technique was used to screen for antibacterial activity against pathogenic strains of E. Coli and S. aurous at a concentration of 0.5 mg/mL. The relevant medicines were used as standards. Comparing the polymers' antibacterial activity to that of the medications controlled, the results indicate an increase the activity.